Mistrust in medicine: the rise and fall of America's first vaccine instituteLanzarotta T, Ramos MA. Mistrust in medicine: the rise and fall of America's first vaccine institute. American Journal of Public Health. 2018;108(6):741–747. doi:10.2105/AJPH.2018.304348
Beginning with the 1813 Act to Encourage Vaccination (against smallpox), this article traces how physicians—in the 19th century and today—have worked to build public trust in vaccination in an American culture suspicious of medical expertise.